Statistical Analysis of Dosimetric Data obtained by 3D Conformal Radiotherapy (3D-CRT) and Volumetric Modulated Arc Therapy (VMAT®) in Prostate Cancer

Meriem Tantaoui, Abdenbi El Moutaoukkil, Mustapha Krim, Ismail Ghazi, Zineb Sobhy, Abdelkrim Kartouni, Hamid Chakir, Jamal Inchaouh, Souha Sahraoui and Hassan Jouhadi

Radiation therapy is one of the treatments used to treat prostate cancer while relying on the principle of irradiating the tumor by sparing healthy tissue. There are different modalities of radiotherapy used to treat this type of cancer, which leads to identifying the difference between them. The purpose of this study is to compare by statistical analysis between 3D Conformal Radiotherapy (3D-CRT) and Volumetric Modulated Arc Therapy (VMAT®) and to give a model of confirmation of the difference between the dosimetric results obtained by each technique, the existence of which has not previously been statistically proven. This is through the use of the Student test for a sample of 14 patients with prostate cancer. This test applied to dosimetric parameters obtained after validation of treatment plans according to each radiotherapy technique. The results of this study indicate that there are significant differences between 3D-CRT and VMAT® in most of the relevant evaluated values of the target response, organs at risk (OARs) and normal tissue savings. VMAT® shows better savings for the latter.

Volume 12 | 05-Special Issue

Pages: 158-165

DOI: 10.5373/JARDCS/V12SP5/20201744